Sponsor   

Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community, medical students, and the medical industry. We will post a workweek daily medical or surgical term, its meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

Click on the link below to subscribe to the MTD newsletter. If you think an article could be interesting to somebody else, click on the mail link at the top of each article to forward it. 

You are welcome to submit questions and suggestions using our "Contact Us" form. The information on this blog follows the terms on our "Privacy and Security Statement"  and cannot be construed as medical guidance or instructions for treatment. 


Click here to subscribe to the Medical Terminology Daily Newsletter

fbbuttons sm

We have 286 guests and no members online


A Moment in History

Dr. Thomas Dent Mütter
Dr. Thomas Dent Mütter (1811-1859)

Dr. Thomas Dent Mütter

(1811-1859)

Thomas Dent Mutter was born on March 9, 1811, in Richmond, VA. His mother died in 1813, and his father died of tuberculosis in 1817. Thomas was orphaned when he was barely 8 years old. His father left him a somewhat meager inheritance and in his early life had to do with less that others with his objectives in life. He was well educated under the tutelage of Robert Carter, his guardian, and in 1824 he started his studies at the Hampden Sidney College of Virginia. He continued with a medical apprenticeship with a Dr. Simms in VA. He was well respected and even at his early age he would do home visits for his medical benefactor with great results. He started medical studies at the University of Pennsylvania, where he earned his MD in 1831. The new young doctor, Thomas Dent Mutter, MD was only 20 years of age.

At the time, Europe was the place to go to if you wanted advanced medical studies. Dr. Mutter had no money, so he applied as a ship surgeon to be able to cross the Atlantic. Once in Europe, he spent time in Paris, where he studied under the tutelage of Dr. Guillaume Dupuytren. He later studied for a short time in England where he met Dr. Robert Liston. Following Dupuytren's teachings, Mutter was fascinated by plastic surgery.

A chance encounter with what was to become his first well-known acquisition of a medical curiosity, Mutter started thinking on how to help those people that were known at that time as “monsters”, patients who the general public did not see, because they did not appear in public. The curiosity in question was a wax reproduction of the face of a French woman who had a “horn” arising from her forehead. This piece is on exhibit at the Mütter Museum.

Back in the United States in 1832, Thomas Dent Mutter changed his last name to give it a more “European” sound and added an “umlaut”, so now he was Thomas D. Mütter, MD. It may also be that he wanted to pay homage to his Scottish-German heritage, who knows? He opened his medical office in Philadelphia and although it took time, eventually he had a thriving practice. One of his specialties was the work on “deformities” so common at the time because of facial scars born out of the use of open fires in houses, and deformities caused by burns and loss of tissue due to chemicals used in local industry. Dr. Mütter is the pioneer of what we call today “Reconstructive Surgery”.

In 1835 he was asked to join the Medical Institute of Philadelphia as an assistant professor of Surgery. He was an instant success. Dr. Mütter was adored by his students because, he would question the students and guide them to discovery instead of just lecturing and leaving. In his Discourse eulogy of Dr. Mütter by Joseph Pancoast he writes:” The power of attracting students near him by his mingled gentleness, energy, and enthusiasm; of fixing their attention by the lucid and methodical arrangements of his Subject, by his clear demonstrations, and sprightly oral elucidations, came so readily to him, and was so early displayed) as to seem almost intuitive.” In 1841 Dr Mütter was appointed Professor of Surgery at the Jefferson Medical College in Philadelphia.

Dr. Mütter had always had poor health, even in childhood, and his dedication to his passion, long hours, took its toll on his body. In 1956 he set sail for Europe and resigned his teaching duties. He was named Emeritus Professor of Surgery. Unfortunately, the trip did not help, and he returned to the US in early 1958. Fearful of another winter in cold Philadelphia, he moved to Charleston, SC, where he died on March 19, 1859.

Dr. Mütter’s story does not end here. He was an avid collector and throughout his short life he had pulled together an impressive collection of medical oddities, samples, and curiosities. Knowing that his life was at an end, he negotiated with the Philadelphia College of Physicians to have them host his collection in perpetuity as well as the creation of a trust fund that would ensure that the public and medical students would have access to this incredible collection. Through the years this collection has increased and is known today as the Mütter Museum of the Philadelphia College of Physicians. I strongly urge our readers to visit this incredible museum. For more information, click here.

Personal notes: In the late 90’s, I attended a meeting of the American Association of Clinical Anatomists.  During the meeting I met Gretchen Worden, who at the time was the Curator of the Mütter museum. Gretchen was inspirational, fun, and a great conversationalist! I had the opportunity to visit Gretchen at the Mütter museum and had the luck to be treated to a “behind the scenes” tour. What an experience! I was saddened to hear that Gretchen Worden passed on August 2, 2004. Still, in my recent visit to the Mütter Museum, I was glad to see a new section at the museum that remembers Gretchen. Her biography can be read here.

I would like to thank Dr. Leslie Wolf for lending me the book by O’Keefe that lead to me writing this article. Dr. Miranda

Sources:
1. “Dr. Mütter’s Marvels: A True Tale of Intrigue and Innovation at the Dawn of Modern Medicine” O’Keefe, C. 2015 Penguin Random House, LLC
2. “A Discourse Commemorative of the Late Professor T.D. Mütter” Pancoast, J. 1859 J Wilson Publisher
3. “Thomas Dent Mütter: the humble narrative of a surgeon, teacher, and curious collector” Baker, J, et al. The American Surgeon, Atlanta 77:iss5 662-14
4. “Thomas Dent Mutter, MD: early reparative surgeon” Harris, ES; Morgan, RF. Ann Plast Surg 1994 33(3):333-8
5. “5 Things I Learned from Thomas Dent Mütter” O’Keefe C.


"Clinical Anatomy Associates, Inc., and the contributors of "Medical Terminology Daily" wish to thank all individuals who donate their bodies and tissues for the advancement of education and research”.

Click here for more information


Rare & Collectible Books at AbeBooks.com 

 

Bicuspid aortic valve

The normal components of the aortic valve are part of the aortic root. The valve is composed of three leaflets, each of which are related to a sinus of Valsalva, and three interleaflet triangles. The anatomy of the aortic root, the aortic valve and the interleaflet triangles of the aortic root have been described in other articles in this website.

A bicuspid aortic valve (BAV) is probably the most common cardiac defect of congenital origin. The prevalence of BAV ranges from 0.9% to 2% in the general population with a 3:1 male-female ratio.

In spite of the anomaly, a BAV may achieve normal valvular function, but this probably does not last, as BAV tend to develop calcifications in the adult leading to valvular disease, dysfunction, valvar stenosis, so complications are common, the most common being dilation of the aortic root and ascending aorta.

Excised bicuspid aortic leaflets
Excised bicuspid aortic leaflets.
Click on the image for a larger version.
 
The etiology of a BAV is commonly accepted as congenital and there are some studies that demonstrate a familial component, but it can appear in families where there is no known history of BAV.

There are several attempts at classifying BAV, as the leaflets that fuse are different, and so is the way of fusion.

There is one rare BAV called “pure”. This purely BAV is a true BAV, composed of two leaflets of similar size where there is no clear fusion line or “raphe” between the fused leaflets (see image). This valve has two well developed interleaflet triangles and the third can be absent or vestigial.  The image depicts the excised calcified leaflets where the left and right coronary cusps are fused.  

Other types of BAV have a well-developed raphe, have two well developed interleaflet triangles and the third may be large or anomalous. The leaflets may also be asymmetrical. The classification of the different types of BAV goes beyond the objective of this article, but they can be studied in the references at the end of this article. There is no doubt that the different types of BAV can cause valvar disease and hemodynamic chaos, so the surgical approach for these may be different, including valve repair, aortic annuloplasty, interleaflet triangle remodeling, and of course valve removal and prosthetic implant, either biological or mechanical.

Clinically, the pathologies related to the function of the aortic valve are stenosis, valvular incompetence, and in some cases intimal aortic dissection, which is a catastrophic complication. Some of these complications are triggered by the calcification of the bicuspid leaflets. Interestingly, although BAV is a congenital disease, only one in fifty children known to have BAV have clinically significant disease by adolescence.

PERSONAL NOTE: I have permission to publish the image in this article… because the bicuspid aortic valve depicted in this article is my own. My personal thanks to the medical and support personnel at the Memorial Hermann Heart & Vascular Institute, in Houston, TX., and my three cardiovascular physicians without whom I would not be back writing this article, Drs. Randall K. Wolf (contributor to this website), Dr. William Ross Brown (cardiologist), and Dr. Tuyen Nguyen, who operated on me. Dr. Miranda.

Sources:
1. “Etiology of bicuspid aortic valve disease: Focus on hemodynamics: Atkins, SA, Sucosky, P World J Cardiol. 2014 Dec 26; 6(12): 1227–1233.
2. “A classification system for the bicuspid aortic valve from 304 surgical specimens” Sievers, HH., Schmidtke, C. J Thorac Cardiovasc Surg 2007;133:1226-33
3. “Bicuspid Aortic Valve Disease” Siu, SC, Silversides, CK. JACC Vol. 55, No. 25, 2010:2789 – 800
4. “Bicuspid aortic valve aortopathy in adults: Incidence, etiology, and clinical significance” Int J Card 2015:1;400-407
5. ”Sutureless valve in freestyle root: new surgical valve-in-valve therapy” Villa E, Messina A  et al. Ann Thorac Surg  2013:96:e155–e157
6.” Sutureless aortic bioprosthesis valve implantation and bicuspid valve anatomy: an unsolved dilemma?” Lona, M, Guichard JB, et al Heart vessels 2016.31:1783-1789


Ligament of Treitz


This is the most popular article on this blog by far!
Look at the hits counter on this article...
Let us know other topics that may interest you in our
"Contact Us" page.


The ligament of Treitz is formed by a fold of peritoneum over the suspensory muscle of the duodenum. This muscle is also known as the "muscle of Treitz" or "musculus suspensorius duodenii". This muscle was first described in 1853 by Dr. Václav Treitz. 

The muscle (see image #1) has an unusual structure in that it is formed by a tendon with two muscular ends  of dissimilar embryological origin and function. The superior muscular component is skeletal (voluntary) muscle and arises as a slip of muscle (Hilfsmuskel) from the right esophageal crus of the respiratory diaphragm, as well as muscular and ligamentous fibers arising in the region of origin of the celiac trunk and superior mesenteric artery. The inferior portion of the muscle is smooth (involuntary) muscle and has been described as continuous with both the longitudinal and circular muscle layer of the intestine at the duodenojejunal junction.

Anterior view of the duodenum and the suspensory muscle of the duodenum
Click on the image for a larger version
Original image by Dr. Václav Treitz
The ligament of Treitz is an anatomical landmark used by anatomists and surgeons to denote the duodenojejunal junction and the point where the small intestine passes from retroperitoneal duodenum to intraperitoneal jeunum. Surgeons use the ligament of Treitz to measure the jejunum to decide where to perform an anastomosis.Click on the gray bar below the image to see the original sketch published by Dr. Václav Treitz in his 1853 publication "Ueber einen neuen Muskel am Duodenum des Menschens" (On a new muscle in the duodenum of man). The 'muscle of Treitz" is marked by an arrow.

It is important to clarify that the term "ligament" in the abdominopelvic cavity has a different meaning and structure from a skeletal ligament found in a joint. For more information click here.

Clinical anatomy, pathology, and surgery of the gastrointestinal tract are some of the many lecture topics developed and delivered to the medical devices industry by Clinical Anatomy Associates, Inc.

Sources:
1.
"Clinically Oriented Anatomy" Moore, KL. 3r Ed. Williams & Wilkins 1992
2. "The origin of Medical Terms" Skinner, AH, 1970
3. "The suspensory muscle of the duodenum and its nerve supply" Jit, I.; Singh, S. J. Anat. (1977), 123, 2, pp. 397-405
4. "Anatomical and functional aspects of the human suspensory muscle of the duodenum." Costacurta, L. Acta Anat (Basel). 1972;82(1):34-46
Image property of: CAA.Inc. Artists: Dr. E. Miranda and D.M. Klein


The interleaflet triangles of the aortic valve

The interleaflet triangles (ILTs) are three triangular regions found in the ventricular aspect of the aortic root. They are bound inferiorly by the virtual basal ring (VBR), laterally by the attachment of the leaflets (the hinge) to the aorta and left ventricular wall (muscular and fibrous), and superiorly by the commissures (site of attachment and meeting of adjacent leaflets) which are usually located at the sinotubular junction, also known as the sinotubular ridge.  

A review of the literature on the topic shows that although many speak of these ILTs, not many authors have clearly defined their boundaries. In fact, some only reserve the term ILT to the triangular region distal to the ventriculoaortic boundary. The description used in this article includes the ventricular wall found between the VBR and the ventriculoaortic junction as well as fibrous components found between these two boundaries. Based on this description, we have developed an image of the ILTs that, to our knowledge is not found in literature. (see accompanying images).

Interleaflet triangles of the aortic valve by MTD
Interleaflet triangles of the aortic valve by MTD.
Click on the image for a larger version.
 
The virtual basal ring is a circular virtual line formed by the nadirs of the three aortic leaflets (cusps). The attachment of the three leaflets create a three-pronged coronet that is useful in defining the interleaflet triangles (see image)

The superior boundary of the ILTs is formed by three commissures, the points where the leaflets meet each other at the sinotubular junction. There are two posterior commissures, right and left. The right-posterior commissure is found between the noncoronary and the left coronary sinuses (of Valsalva). An important point about this commissure is that it is situated above the midpoint of the septal (anterior) leaflet of the mitral valve. The left-posterior commissure is found between the left and the right coronary sinuses. The anterior commissure is located between the right and the noncoronary sinus close to the membranous interventricular septum.

Based on the above description, there are three interleaflet triangles:

a. Right (posterior), left (posterior), and anterior. The right posterior ILT is located between the noncoronary and the left coronary sinuses, and just as the commissure at its apex, is located at the midpoint of the septal (anterior) leaflet of the mitral valve. Also, the superior aspect of this ILT is related to the transverse pericardial sinus.

b. The left posterior ILT is located between the right and the left coronary sinuses, and is lies immediately behind the right ventricular outlet.

c. The anterior ILT is found between the right and the noncoronary sinuses. It is related to the membranous septum and the right fibrous trigone, forming part of the central fibrous body (skeleton) of the heart. This ILT is a good anatomical landmark to the location of the bundle of His and the left bundle branch, both components of the conduction system of the heart. These structures can be compressed during the implantation of an aortic or mitral valve, causing transitory or permanent cardiac conduction problems.

The ILTs are important in the normal physiology and hemodynamics of the aortic valve. A small ILT will affect the diameter of the valve and the movement of the leaflets, causing stenosis. This is the case in bicuspid aortic valves where the fusion of two of the leaflets leads to the reduction in size of the ILT normally found between these two fused leaflets.

Since they are located within the functional portion of the left ventricle, the ILTs are subject to the pressures of the ventricle and can be areas that develop aneurysms.

Because of their importance in the hemodynamics of the aortic valve, new procedures and medical devices that reshape the ILTs are being developed. This is specially important in the case of a bicuspid aortic valve, where the interleaflet triangles may be abnormal.

Interleaflet triangles of the aortic valve by Sutton
Interleaflet triangles of the aortic valve by Sutton.
Click on the image for a larger version.
Further to the images that are depicted in this article, the lower image is the classic image of the interleaflet triangles by Sutton (1995). As you can see, the base of the triangles is shown straight with no clear boundary, and it seems as though they are related to the ventriculoaortic junction.  The nadirs are not used as a point of reference. The upper image (developed by us and based on Sutton's original sketch) clearly shows the extent of the ILTs as well as their relation to the three landmarks that define the aortic root: The virtual basal ring, the ventriculoaortic junction, and the sinotubular junction.

NOTE: The pulmonary valve also has interleaflet triangles, with a somewhat similar description, but since they are under low pressure they do not develop or are cause of pathology as the ILTs of the aortic valve.

Sources:
1. The Anatomy of the Aortic Root: Loukas, M et al. Clinical Anatomy 27:748–756 (2014)
2. “Extracardiac aneurysm of the interleaflet triangle above the aortic-mitral curtain due to infective endocarditis of the bicuspid aortic valve.” Hori D, et al. Gen Thorac Cardiovasc Surg. 2008 Aug;56(8):424-6
3. “Anatomy of the aortic root: implications for valve-sparing surgery” Efstratios I. Charitos, HS. Ann Cardiothorac Surg 2013;2(1):53-56
4. “The Forgotten Interleaflet Triangles: A Review of the Surgical Anatomy of the Aortic Valve” Sutton JP, et al Ann Thorac Surg 1995;59:419-27
5.” The aortic interleaflet triangles annuloplasty: a multidisciplinary appraisal” Mangini, A., et al. European Journal of Cardio-Thoracic Surgery, Vol. 40:4, 2011, 851-857
6. “Structure and Anatomy of the Aortic Root” Ho, SH., Eur J Electrocar 2009 10; i3-i10
7. “In vitro study of the aortic interleaflet triangle reshaping” Vismara, R Journal of Biomechanics; 47:2; 2014. 329-33


The aortic root and the aortic valve (2)

This article is a continuation of: The aortic root and the aortic valve (1)

The aortic valve is formed by three semilunar leaflets which are very thin as to be almost transparent.  The attachment of the leaflets is complex, as part of them attaches to ventricular wall, part attaches to the sinusal arterial wall, and even part of them attaches to the membranous interventricular septum and other fibrous structures. Loukas et al state that at “least one third of the circumference of the aortic root is supported by fibrous tissue rather than ventricular musculature”

Each of the three aortic leaflets has a semilunar attachment and shape (hence the term “semilunar valve” used for both the aortic and pulmonary valve, as they have similar shape). The attachment of these three leaflets create a continuous line where the highest points are the three locations where the leaflets attach at the STJ, and the three lower points or “nadirs” form an edge shaped like a three-pronged “coronet”. This coronet is called by many the “anatomical anulus” of the aortic valve, as this is where the fibrous skeleton of the heart forms the “hinges” of the aortic valve.

Aortic root and aortic valve
Aortic root and aortic valve.
Click on the image for a larger version.
 
The leaflets of the aortic valve (as well as those in the pulmonary valve) have a tissue excrescence that can become quite hard at the point where the three leaflets touch on each heartbeat. These are the nodules of Arantius, named after Giulio Cesare Aranzio (1530 – 1589). As a side note, the nodules of the pulmonary valve have a different name. Distally, the aortic leaflets may present a very thin extension that may be cribriform (not shown in the sketch). These are called the lunulae (singular: lunula) as they look like a sliver of moon.

The second component of the base of the aortic root is a ring defined by the lowest portion of each leaflet, the nadir. This ring is called the “virtual basal ring”, is found within the left ventricle and is used as a surgical reference for aortic valve replacement implants.

The three leaflets are found within three dilations of the aortic root, each one called a “sinus of Valsalva”, which extend between the virtual basal ring inferiorly and the STJ superiorly. The presence of the sinuses of Valsalva permits “fluttering” of the open aortic leaflets in ventricular systole. This fluttering of the leaflets allows blood to flow into the sinuses and into the coronary arteries during ventricular systole.

Aortic valve may present with different number of leaflets, as in the case of a bicuspid aortic valve.

The shape of the attachment of the leaflets create two distinct situations:

First, there is a portion of the ventricle related to the leaflets where the ventricle acts as an artery, the aorta. These areas are found inside the sinuses of Valsalva.

Second, there are triangular areas of the aortic root (the interleaflet triangles) where the aortic wall is within the left ventricle and submitted to the pressures and hemodynamics of the left ventricle. These interleaflet triangles have been involved in aneurysms. For simplicity, these interleaflet triangles are not shown in the sketch and are the subject of a separate article in this website.

Note: The image depicts only one complete aortic leaflet. The other one has been transected to show the sinus of Valsalva and the third has been removed to show the attachment or "hinge" of the leaflet. For an anatomical image of the aortic valve click here.

Sources:
1. The Anatomy of the Aortic Root: Loukas, M et al. Clinical Anatomy 27:748–756 (2014)
2. “Extracardiac aneurysm of the interleaflet triangle above the aortic-mitral curtain due to infective endocarditis of the bicuspid aortic valve.” Hori D, et al. Gen Thorac Cardiovasc Surg. 2008 Aug;56(8):424-6
3. “Anatomy of the aortic root: implications for valve-sparing surgery” Efstratios I. Charitos, HS. Ann Cardiothorac Surg 2013;2(1):53-56
4. “The Forgotten Interleaflet Triangles: A Review of the Surgical Anatomy of the Aortic Valve” Sutton JP, et al Ann Thorac Surg 1995;59:419-27


The aortic root and the aortic valve (1)

The term “aortic valve” refers to the three leaflets (or cusps) components that allow passage of blood from the left ventricle to the ascending aorta during ventricular systole, while at the same time preventing regurgitation or reflux of blood back into the ventricle during ventricular diastole. In reality, the “valve” is only a component of a larger structure called the “aortic root”. This article will describe the components of the aortic root and the aortic valve.

The ascending aorta presents with two distinct segments. The proximal segment is a dilated portion called the aortic root. The distal portion is known as the tubular portion of the ascending aorta. The boundary between these two portions is the [sinotubular junction (STJ). Some authors will recognize as the ascending aorta only the tubular portion.

The aortic root is that portion of the ventricular outflow tract and proximal aorta that supports the leaflets of the aortic valve. It is a functioning unit with relations both to the to the aorta and to the left ventricle, and it is here where in most cases we find the ostia of the right and left coronary arteries.

Aortic root and aortic valve
Aortic root and aortic valve.
Click on the image for a larger version.
 
The aortic root is composed of the three dilated sinuses of Valsalva, two of which give origin to the coronary arteries (right and left), three leaflets (or cusps), and the interleaflet triangles. While the distal boundary of the aortic root is clearly defined (the STJ), the proximal boundary is not as clear and is difficult to define. The STJ is defined by the apices of the three aortic leaflets as well as a clear line that appears as the aorta passes from the dilations of the sinuses of Valsalva to the well-defined tubular portion of the ascending aorta.

This proximal boundary is defined clinically by two circular regions: the ventriculoaortic ring distally and the virtual basal ring proximally.

The ventriculoaortic ring is a circular region formed by the left ventriculoaortic junction (the point where the aorta anchors on the left ventricle), and fibrous tissue of both the “cardiac skeleton” and the membranous interventricular septum. It is also called the “surgical anulus”. This is the area where a surgeon will anchor an aortic replacement valve.

Continued here: The Aortic Root and the Aortic Valve (2)

Note: The image depicts only one complete aortic leaflet. The other one has been transected to show the sinus of Valsalva and the third has been removed to show the attachment or "hinge" of the leaflet. For an anatomical image of the aortic valve click here.

Sources:
1. The Anatomy of the Aortic Root: Loukas, M et al. Clinical Anatomy 27:748–756 (2014)
2. “Extracardiac aneurysm of the interleaflet triangle above the aortic-mitral curtain due to infective endocarditis of the bicuspid aortic valve.” Hori D, et al. Gen Thorac Cardiovasc Surg. 2008 Aug;56(8):424-6
3. “Anatomy of the aortic root: implications for valve-sparing surgery” Efstratios I. Charitos, HS. Ann Cardiothorac Surg 2013;2(1):53-56
4. “The Forgotten Interleaflet Triangles: A Review of the Surgical Anatomy of the Aortic Valve” Sutton JP, et al Ann Thorac Surg 1995;59:419-27


The lost influence of Andreas Vesalius on eponymic anatomy

Andreas Vesalius Bruxellensis (1515-1564) is considered to be the father of modern anatomy, remembered because an illustrious life and by his book “De Humani Corporis Fabrica, Libri Septem” published first in 1543. Scores of books, translations, articles, and analyzes of his work have been published in the over 500 years since his birth.

With such an incredible pedigree we would expect his name to be attached to more than a few anatomical structures, many of which were first described in his opus magnus, the “Fabrica”, I wonder why this is not so. It is true that modern anatomy is trying to move from eponyms to more descriptive anatomical terms. Still, there are many that will not go away, as is the famous ligament of Treitz, or the sphincter or Oddi.

Today there is only one recorded eponym for Andreas Vesalius, the os vesalianum, a rare accessory bone in the foot located proximally to the base of the fifth metatarsal. It is usually asymptomatic, but in rare cases it can cause pain. It is formed by the failed fusion of the secondary ossification center of the fifth metatarsal.

Reviewing history, I was able to find other references to Andreas Vesalius eponyms or potential eponyms, now in disuse or misnamed:

Andreas Vesalius Bruxellensis
Suspensory ligaments of the mammary gland. Although first described by Vesalius in the Fabrica, these structures are named after Sir Astley Paston Cooper (1768 -1841), almost 300 years after being described by the great anatomist, who called them a “fleshy membrane” that stretched between the pectoral fascia and the skin.

- The vermiform appendix. Although called by many just “the appendix”, this structure is mentioned, but not named, by Jacobo Berengario da Carpi in 1524. It was Andreas Vesalius who first described it as an appendix, suggested it looked like a worm (Lat: vermis) calling it the “vermiform appendix”.

- The ligamentum suspensorium Vesalii or crural arch. First described by Giovanni Baptista Morgagni (1682-1771), it was named in honor of Vesalius by Dr. Laurentii (Lorenz) Heisters in his “Compendium Anatomicum” published in 1756. Other authors point to Gabrielle Fallopius as the first to describe this structure in 1561, although he did publish later than Vesalius (1543). Although named after Vesalius, it was later named after Francois Poupart who described it in 1695. You probably know this structure as the inguinal ligament.

-The ligamentum teres femoris. The round ligament of the femur was also first described by Vesalius in 1543.

NOTE: If you have other structures that have been named after Vesalius, please let me know by clicking here.

Sources:
1. “A Rare Cause of Foot Pain with Golf Swing. Symptomatic Os Vesalianum Pedis—A Case Report” Petrera, M et al. Sports Health. 2013 Jul; 5(4): 357–359.
2. “Andreas Vesalius’ 500th Anniversary: First Description of the Mammary Suspensory Ligaments” Brinkman RJ, Hage, JJ. World J Surg (2016) 40:2144–2148
3. “Compendium Anatomicum” Heisters, L. 1756 (German)
4. “Anatomy: An Encyclopedic Reference to the Language of Anatomy and Neuroanatomy. It Provides the Fascinating Origin of Terms and Biographies of Anatomists/Physicians Who Originated Them” Bergman, RA, Afifi, AK 2016